The movie reboots the modern film series that began with 2002's "Spider-Man" and whose three movies netted around $2.5 billion at global box offices for its makers, Marvel Studios and distributor Sony Pictures.
After those earlier films, Sony cut the budget for its fourth installment and replaced Maguire with Garfield, who played a supporting role in Facebook movie "The Social Network,"
The story of young love helped lure female viewers, who made up 42 percent of the audience, according to Sony. Seventy-three percent of reviews compiled on website Rotten Tomatoes recommended the movie.
"This is a film that had something for women," said Rory Bruer, president of worldwide distribution for Sony Pictures Entertainment. "Gwen Stacy is a pretty strong woman in her own right, and the two of them had great chemistry on screen."
The new "Spider-Man" cost about $215 million to produce, plus tens of millions more for marketing. The film is Sony's second big-budget hit this summer, following the success of alien comedy "Men in Black 3" in May.