The elegant Ephron, known for habitually dressing in black, urged aging friends and readers to make the most of their lives.
"You should eat delicious things while you can still eat them, go to wonderful places while you still can ... and not have evenings where you say to yourself, 'What am I doing here? Why am I here? I am bored witless!'" she told Reuters in a 2010 interview while promoting the book.
She began her career as a journalist but transitioned into movies, leaving behind a legacy of more than a dozen films, often featuring strong female characters, that she either wrote, produced or directed. She was nominated for three Academy Awards for "Harry Met Sally," "Sleepless in Seattle" and the drama "Silkwood" with Meryl Streep playing an anti-nuclear activist.
Ephron also wrote for the stage, authoring the 2002 play "Imaginary Friends" about the rivalry of authors Mary McCarthy and Lillian Hellman, and "Love, Loss and What I Wore," with her sister Delia, in 2009.