NBA playoffs on Monday night saw Oklahoma City crush the Lakers, while Philadelphia beat Boston in Game 2 of their Eastern Conference semifinal.
In the first matchup between the teams since World Peace struck James Harden with an elbow on April 22 to draw a seven-game suspension, the Thunder hit back to take a 1-0 series lead.
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"I just tried to come out aggressive, we hadn't played in a while and I had some good legs underneath me," Westbrook told reporters.
The Thunder swept their first-round series and had more than a week off while the Lakers just wrapped up a tough seven-game series two days ago.
Kobe Bryant and Andrew Bynum both had 20 points, but the Lakers fell behind by 15 at halftime and the deficit ballooned to 30 in the third as the visitors struggled to cope with Oklahoma City's foot speed and athleticism.