The meeting with the NRA is one of three Biden has scheduled for Thursday, as he prepares to make recommendations on gun policy by the end of the month. Besides the NRA, Biden and other officials are meeting with sportsmen and wildlife interest groups, as well as people from the entertainment industry.
The NRA, the nation's largest gun-rights group, has blocked gun-control efforts in the past and is opposing any new ones.
Shortly after last month's shooting in Newtown, Conn., President Barack Obama tasked Biden with heading a commission to come up with recommendations on gun policy by the end of January. Obama supports steps including reinstating a ban on assault weapons and high-capacity ammunition magazines and closing loopholes that allow many gun buyers to avoid background checks.
Biden, who met with representatives of victims groups and gun-safety organizations Wednesday, said officials are considering steps that could "take thousands of people out of harm's way" and improve the safety of millions more.
"I want to make it clear that we are not going to get caught up in the notion that unless we can do everything, we're going to do nothing," Biden told groups including the Brady Campaign to Prevent Gun Violence. "It's critically important we act."