Egana, a former Socialist councillor in northern Spain, jumped to her death from her fourth-floor flat as bailiffs were trying to evict her under foreclosure laws.
Speaking in Brussels, de Guindos said action was vital to avoid evictions at a time when huge numbers of homes, built during a frenetic property boom before 2008, lie unoccupied.
"In Spain right now, we have nearly a million empty housing units. In this situation, the government and the economy ministry ... has to take steps so that no family in good faith goes without a home. This is our commitment," he said.
Public pressure prompted Prime Minister Mariano Rajoy to call for officials from his conservative People's Party and the opposition Socialists to speed up negotiations on reforming the eviction laws during talks on Monday.