He said the woman had remained in an extremely critical condition since Thursday when she was flown to Singapore from India.
"Despite all efforts by a team of eight specialists in Mount Elizabeth Hospital to keep her stable, her condition continued to deteriorate over these two days. She had suffered from severe organ failure following serious injuries to her body and brain. She was courageous in fighting for her life for so long against the odds but the trauma to her body was too severe for her to overcome."
The woman and a male friend, who have not been identified, were traveling in a public bus after watching a film on the evening of Dec. 16 when they were attacked by six men who took turns to rape her. They also beat the couple and inserted an iron rod into her body. Both of them were then stripped and thrown off the bus, according to police.
Indian police have arrested six people in connection with the attack, which left the victim with severe internal injuries.
Indian High Commissioner, or ambassador, T.C.A. Raghanvan told reporters that the scale of the injuries she suffered was "very grave" and in the end it "proved too much.
He said arrangements are being made to take her body back to India
The crime shocked Indians, who have come out in their thousands for almost daily demonstrations, demanding stronger protection for women and death penalty for rape, which is now punishable by a maximum life imprisonment.